Synthesis and Solid State Pharmaceutical Centre

Ireland: Southern (Ireland)

Overview

Mission/Objectives of the cluster organisation

The Synthesis and Solid State Pharmaceutical Centre (SSPC), a Global Hub of Pharmaceutical Process Innovation and Advanced Manufacturing, funded by Science Foundation Ireland and industry, is a unique collaboration between 24 industry partners, 9 research performing organisations and 12 international academic collaborators.

The SSPC transcends company and academic boundaries and is the largest research collaboration in Ireland, and one of the largest globally, within the pharmaceutical area. The role of the SSPC is to link experienced scientists and engineers in academia and the pharmaceutical industry, to address critical research challenges.

The SSPC leads the way for next generation drug manufacture and spans the entire pharmaceutical production chain from synthesis of the molecule, to the isolation of the material, and the formulation of the medicine. The aim of the SSPC is to deliver industry relevant solutions, which result in job growth and retention within the pharmaceutical industry in Ireland…
University of Limerick Physical Properties, Polymorphism, Chemical Engineering, Modelling and CFD
University College Cork Synthetic Organic Chemistry & Pharmaceutics
University College Dublin Chemical Engineering
Trinity College Dublin Pharmaceutics, Spray-Drying & Milling
National University of Ireland Galway Analytics & Chemometrics
Dublin City University, biomedical diagnostics, biofermentation process analysis, separation science and marine monitoring
Waterford Institute of Technology, drug delivery, pharmaceutical analysis, sensor technologies, biomedical science and molecular biotechnology, X-ray Microtomography, Finite Element Modeling & Microwave processing and material research
Athlone Institute of Technology, Industrial Polymer Solutions and Design, rapid prototyping fabrication, polymer processing, physical and mechanical testing, analytical chemistry, surface and elemental analysis

. Online catalogues and repository:

Online catalogue of infrastructure (Access to Third Level Analytical Services – ATTLAS, www.attlas.ie)

Online national repository showcasing the research capabilities relevant to the (Bio)Pharma sector

(www.therapeutics.ie

State of the art Crystallisation, Isolation and Drying Test-Bed which is the first of its kind globally:  It will be utilised regularly for training, moving away from traditional didactic methodologies towards the ‘learning factory model’, and additionally incorporating significant elements of problem-based learning.

The Biological Processing Testbed, BioPOINT: This research infrastructure will bridge the current technology gap between industrial scale manufacturing and academic research and development for novel biological applications. BioPOINT will engage industry with academics in collaborative research in biopharmaceutical bioprocess problem solving and innovation to drive bioprocess R&D directly enhancing Irish BioPharma activities…. Yes. service.

Sectors
Technology

Biophotonics research group

Belgium: Flemish Region

Overview

Mission/Objectives of the cluster organisation

The Biophotonics group investigates the interaction of light with biological systems to develop innovative sensors for rapid and non-destructive characterisation and monitoring of biosystems. 

We have a long tradition in working together with industry -SMEs as well as large companies- to translate our knowledge into workable solutions. Our clients come from very diverse fields, ranging from food companies over high tech sensor technology providers to large agricultural equipment manufacturers.  

The services we offer cover a large range of activities, including consultancy, complete R&D projects and access to top notch biophotonics equipment.
Our unique and broad range of high-end equipment is an crucial basis for performing successful research and development tasks.  Our main equipment categories are:

Dark Optics Room (supercontinuum laser, double integrating spheres, laser scattering
Hyperspectral imaging setups (VIS-NIR, SWIR, line scanning system, snapshot cameras) 
Active thermography (high-end cooled camera, microbolometers, pulsed and lock in system, flash excitation, halogen sources)
Spatially resolved spectroscopy (SRS probes, translation stage, large range on spectrophotometers)
Data acquisition systems (National instruments DAQ, PXI, SICK) 
Specialised data analysis software (JMP, The Unscrambler, Matlab, Python, SAS, R)
Mechanical properties measurements (Universal Testing Machine, Rheometer, Impact pendulum)
Vibration test rigs (up to 7500kg)

. The Biophotonics group provides services at several levels to industry.  Our main activities are:

Providing access to outstanding equipment
Complete bilateral R&D projects - from proof of concept studies to demonstrators
Consultancy services - providing academic expertise in biophotonics
Providing information on funding opportunities - local, national and international
Support customers to perform very reliable and efficient experiments, and help them analyzing the data
Providing in-company training on biophotonics and advanced data analysis

. Yes. service.

Sectors
Technology

Institute of Technical Physics and Materials Science (MFA)

Hungary: Pest

Overview

Mission/Objectives of the cluster organisation

The main tasks of the Institute of Technical Physics and Materials Science (MFA) are: research on nanometer scale functional materials exploring their physical, chemical and biological properties, as well as the exploitation of these properties in the development of integrated nano/microsystems, sensors, and non-destructive characterisation techniques. Important task of the MFA is the technical support of the SMEs and the university education, the utilisation of the research infrastructure for serving the needs of graduate and postgraduate education (TDK, BSc, MSc, and PhD) in the scheme of an open access laboratory.

MFA hosts 5 scientific departments and 2 groups:

Microtechnology Department (www.mems.hu, www.biomems.hu, www.nems.hu)

The main task of the Microtechnology Department is the multidisciplinary research on sensors, the realisation of functional nano- and microsensors based upon novel sensing principles, their validation and elaboration of the adequate processing technology.

In the… The Institute of Technical Physics and Materials Science (MFA)  Microtechnology Department runs two 300 m2 + 160 m2 clean labs (Class 100-10000) comprising a complete Si-CMOS processing line and a mask shop, unique facility in Hungary. The technology allows to manufacture layers, patterned structures and devices with line resolution of 1 µm by optical and down to 20 nm by e-beam lithography on 3” and 4” Si and glass wafers. (http://www.mems.hu)

Competences (available also for our industrial and academic partners and customers):

High temperature annealing, diffusion and oxidation;
Ion implantation;
Rapid Thermal Treatment;
Low Pressure Chemical Vapor Deposition of poly-Si, SiO2 and Si3N4 layers;
Low Temperature Chemical Vapor Deposition;
Atomic Layer Deposition;
Physical Vapor Deposition – Electron beam evaporation, DC and RF Sputtering;
Reactive Ion Etching, Deep Reactive Ion Etching;
Photolithography with back-side alignment and Nanoimprinting;
E-beam lithography;
Nanopatterning…. Services provided by our laboratories:

High temperature annealing, diffusion and oxidation;
Ion implantation;
Rapid Thermal Treatment;
Low Pressure Chemical Vapor Deposition of poly-Si, SiO2 and Si3N4 layers;
Low Temperature Chemical Vapor Deposition;
Atomic Layer Deposition;
Physical Vapor Deposition – Electron beam evaporation, DC and RF Sputtering;
Reactive Ion Etching, Deep Reactive Ion Etching;
Photolithography with back-side alignment and Nanoimprinting;
E-beam lithography;
Nanopatterning, deposition and etching by Focused Ion-Beam;
Wafer-bonding;
Wet chemical treatments;
Electro-chemical porous Si formation;
Mask design, laser pattern generator;
Polymer (PDMS, SU8, Polyimide) structuring by photolithography and micro-molding techniques;
Chip dicing, packaging especially for sensor applications; 
Materials and structural analysis & characterization:, SEM, FIB, EDX, Atomic Force Microscopy, Electrochemical Impedance Spectroscopy, Stylus Profiler;
Electrical and…. Yes. service.

Sectors
Technology

CENTRUM INDUSTRIAL IT (CIIT)

Germany: North Rhine-Westphalia

Overview

Mission/Objectives of the cluster organisation

In the CENTRUM INDUSTRIAL IT (CIIT) the cooperation between industry and science being frequently demanded is actually put into practice. The CIIT is Germany’s first sciene-to-business-center in the field of Industrial Automation. Under one roof companies acting autonomously on the market and research institutes work and research cooperatively on the linkage between information and automation world.

The field of automation technology is the innovation driver for machine and plant engineering. Germany’s core industry, thus playing an essential part in securing Germany’s position as an important economic location. In joint research projects, within the framework of applied basic research, new technologies for the factory of the future are developed in the CIIT.

A Strong Network – Beyond the Boundaries of the Building
Main drivers and actors from industry and science are, apart from the Institute Industrial IT (inIT) of the OWL University of Applied Sciences and the Fraunhofer Application Center… Solutions for Intelligent Automation are jointly researched and developed at CIIT - either in collaborative research projects or at the integrated laboratories (e.g. Big Data Lab, Lab for Cyber Security in Production, Lab for Discrete Systems).

At SmartFactoryOWL, an initiative of the Fraunhofer Society and OWL University of Applied Sciences, technologies for Intelligent Automation are researched, tested and demonstrated.
. ·  Various working groups (e. g. Intelligent Networking, Data Analysis, Human-Machine-Interaction)

·  Industry-on-Campus-Model

·  practice-oriented studying in collaboration with the research institutes under the roof of CIIT
. Yes. service.

Sectors
Technology

Cybernetics Lab IMA & IfU

Germany: North Rhine-Westphalia

Overview

Mission/Objectives of the cluster organisation

The Cybernetics Lab IMA & IfU is an interdisciplinary institute consortium at the RWTH Aachen University assigned to the Faculty of Mechanical Engineering. It is composed of the Institute of Information Management in Mechanical Engineering (IMA) and the Associated Institute for Management Cybernetics e.V. (IfU). 

The aim of the participating institutes is to implement and professionalise inter- and transdisciplinary methods in research and teaching, and to conduct research on current scientific problems. 

The Cybernetics Lab was headed by Prof. Sabina Jeschke until November 2011 and is currenty lead by the deputy heads Prof. Ingrid Isenhardt and Dr. Frank Hees. Managing directors are Prof. Dr. Tobias Meisen (IMA - Information Management), Dr. Max Haberstroh (IMA - Knowledge Management) and Dr. René Vossen (IfU). The former head of the Cybernetics Lab Prof. Klaus Henning supports the as senior advisor. 

Research topics include distributed artificial intelligence, robotics and automation, traffic &… The Cybernetics Lab IMA/ZLW & IfU currently employs an interdisciplinary staff of 200 and technical equipment as well as a broad method spectrum in teaching and organization development, including:

A set of industrial robots (like six axe ABB, Robotino, Pepper, NAO) and equipment
Computer cluster for computational analytics and machine learning tasks
Virtual Theatre and VR technology

. We provide a broad range of services for Industry, including solutions for Industry 4.0, production process organisation and integration of production into Smart Cities. Furthermore, our services include custom-made solutions for organisation development in the areas of innovation, knowledge management and communication processes, as well as training of academic personnel.

Scientific and technological evaluation
Market Studies / Initial Design / Simulation
Component and process development and testing
Prototype / demonstrator development and testing
Custom made solutions for organization development and consulting
School Labs and
seminars and individual coaching for academic personnel

. Yes. service.

Sectors
Technology

Institute of Photonics

Finland: North and East Finland

Overview

Mission/Objectives of the cluster organisation

The Institute of Photonics coordinates all photonics activity within the University of Eastern Finland (UEF).

Researchers come from the Department of Physics and Mathematics, the Department of Environmental and Biological Sciences and School of Computing in collaboration with the Department of Chemistry. 

The photonics research personnel consist of over 20 professors and visiting professors, ca. 30 senior scientists and post docs, and over 30 PhD and ca. 40 MSc students. It is the largest academic unit of photonics in Finland. It is internationally well-recognized, for example, for its contributions to diffractive and micro-optics and nanophotonics (design, manufacturing, and applications), guided-wave optics, optical coherence theory, nonlinear optics, and polarization optics as well as spectromics (imaging plants and environment) and spectral color research. It has a long history on strong collaboration with industry within, e.g. TEKES (Finnish Funding Agency for Technology and Innovation) programs… Characterization laboratory

LEO 1550 electron microscope
Dektak 150+ surface profiler
Wyko NT9300 optical profiler
AutoProbe M5 atomic force microscope

Femtosecond laser laboratory

Quantronix Integra-C 3,5mJ femtosecond laser
CDP TISSA 50 femtosecond laser
Grenouille FROG beam analyzer
CDP ExciPro pump-probe spektrometer
Ekspla THz spektrometer

Lithography laboratory

Electron beam patterning tool EBPG5000+ES
Obducat Eitre 3 nanoimprint tool
Plasmalab 100 ja 80 reactive ion etching tools
Kurt J. Lesker LAB 18 Physical Vapour Deposition
Beneq TFS-200 Atomic Layer Deposition
PTMTEC R2R100UV roll-to-roll printer
Disco DAD3240 wafer dicing saw

3D printing laboratory

Custom-made 3D printer based on Luxexcel’s Printoptical© technology (special inkjet printing technology)
Ultimaker 3 printer based on Fused Deposition Modeling (FDM) / Material extrusion
Redsail X700 laser cutter

Nanocarbon laboratory

Plasma-assisted CVD facility
Hot…. Institute of Photonics provides various kinds of services to industry from training and feasibility studies to prototyping, development and testing as well as innovation on topics focused on its core research topics on photonics. International MSc and PhD students are available for Thesis and interim work in industry all over Europe. Institute of Photonics is active partner in various industrial programs as well as direct contract research with national and international companies.
. Yes. service.

Sectors
Technology

Materials Industrial Research & Technology Center S.A.

Greece: Attica

Overview

Mission/Objectives of the cluster organisation

MIRTEC S.A. - Materials Industrial Research and Technology Development Centre, is a technological Center, active in Applied Research, Technological Development, Certification and Quality Control in a wide range of materials and products.

The company was founded by the merge of three renowned Greek technological centers with over 25 years of experience:

MIRTEC S.A. - CERECO S.Α. - CLOTEFI S.Α.

while the new unified MIRTEC incorporates the certification activities and the laboratories of the Greek Standardisation Organisation (ELOT S.A.).

Our mission is to support industry through leading edge technology and transfer knowledge to our clients, thus improving their competitiveness and competence by adding value to their products.

MIRTEC is the only Hellenic Certification Body with own Laboratories for testing and analysis of materials and products;, this enables our capabilities of offering integrated solutions to our clients.
The systematic collaboration and communication with high respected… The « Industrial Research, Technological Development and Laboratory Testing, Certification and Quality Societe Anonyme », shortly MIRTEC S.A., has its headquarters in Volos and has branches and offices in Greece (Athens, Thessaloniki, Volos and Thiva), in China (Shanghi), while also has an extensive network of experienced associates that covers Greece, Cyprus, Turkey and Romania.

The company’s headquarters are located in the First Industrial Area of Volos and cover an area of 7.500 m2 of indoor facilities on a land plot of 32 acres. Seven of MIRTEC laboratories are located in these premises where testing for a wide range of metal and metallurgical materials is performed, including chemical analysis.

The Thiva branch (former CERECO) is housed in the privately owned building complex which is located on the 72nd km of the Athens-Lamia National Road in Ritsona on a total surface of 3.100 m2. On these premises are located 4 labs and designated areas for industrial testing, conference rooms, lecture halls…. Laboratory Testing

MIRTEC SA has specialized laboratories acknowledged by the National Accreditation System (ESYD S.A.) according the requirements of ELOT EN ISO/IEC 17025 and up- to-date equipment of the latest technology so that it can check a wide range of industrial and consumer products, organic and inorganic materials, which include agricultural products, surface and ground water, irrigation and potable water, solid and liquid waste. The vast experience of the EVETAM laboratories allows the prospect of internal processes (in-house) and specialized analysis depending on the requirements and needs of each customer.

Metallic & Metallourgical Materials Laboratories

Mechanical Testing Laboratory

A number of tests, such as tensile, compression, impact, bend, creep, fatigue and hardness tests are carried out, mainly at metallic materials. The laboratory, in some cases, has the possibility to perform such kind of tests at non metallic materials as well. 

Non Destructive Testing Laboratory

…. Yes. service.

Sectors
Technology

Catalan Institute of Nanoscience and Nanotechnology

Spain: Catalonia

Overview

Mission/Objectives of the cluster organisation

The Catalan Institute of Nanoscience and Nanotechnology (ICN2) is a non-profit Foundation, and one of the centres of the CERCA Institution. Its Patrons are the Generalitat de Catalunya, CSIC (Consejo Superior de Investigaciones Científicas) and the Universitat Autònoma de Barcelona. It was created with the founding objective of becoming a world-renowned centre for nanoscience and nanotechnology research. Its mission is to achieve scientific and technological excellence in these fields. All its human and economic resources are dedicated to achieving this mission. We do so by incubating new fundamental knowledge and ideas, and facilitating the adoption and integration of nanotechnologies into society and industry. To this end, research at ICN2 encompasses: (i) Basic science, primarily via European and national collaborative projects, including frontier areas, and (ii) Technology: in areas of in-house expertise and in conjunction with industry. Therefore, ICN2 interacts closely with universities, research… • Microscopes
o Environmental SEM: FEI Quanta 650 FEG ESEM
o High Resolution SEM: FEI Magellan 400L XRSEM
o High resolution TEM: FEI Tecnai F20 HR(S)TEM

• Sample preparation
o Leica ACE 600 Sputter Coater
o Leica Optical Microscopes
o Well 3242 Diamond Wire Saw
o Struers Minitom Diamond Disk Saw
o Struers Labopol Polishing System
o Allied Multiprep Precision Polishing System
o Gatan Precision Ion Polishing System (PIPS)
o Fischione 1020 Plasma Cleaner
. -Characterisation of physical, chemical, electromagnetic and toxicological properties of nanoparticles, nanostructures and nanomaterials.
—Nano- and micro-encapsulation of substances using a wide range of materials and techniques.
—Development and manufacturing of state-of-the-art of organic and inorganic nanoparticles as well as conjugation “a –la-carte” at laboratory and pilot plant scale for multiple industrial and research applications and their complete physical and chemical characterisation.
—Micro and nano-fabrications: metallisation, lithography, nanoimprinting, self-assembling, Dip Pen Nanolithography, etc. of a wide range of materials and applications and metrology services.
—Development of specific customized biosensors for medical diagnostics, environmental monitoring, food quality control, safety and security applications.
—Consulting and advice on science and technology is available upon request.
. Yes. service.

Sectors
Technology

FOUNDATION for Research and Technology-Hellas (FORTH)

Greece: Crete

Overview

Mission/Objectives of the cluster organisation

The Foundation for Research and Technology-Hellas (FORTH), established in 1983, is one of the largest research centers in Greece with well organized facilities, highly qualified personnel and a reputation as a top-level research foundation worldwide. FORTH reports to the General Secretariat for Research and Technology of the Hellenic Ministry of Education, Research and Religious Affairs. The Foundation, with headquarters in Heraklion, includes six Research Institutes in different parts of the country:

In Heraklion

Institute of Electronic Structure and Laser (IESL)
Institute of Molecular Biology and Biotechnology (IMBB)
Institute of Computer Science (ICS)
Institute of Applied and Computational Mathematics (IACM)

In Rethymnon

Institute for Mediterranean Studies (IMS)

In Patras

The Institute of Chemical Engineering Sciences (ICE-HT)

Also, in Ioannina operates the Department of Biomedical Research under the Institute of Molecular Biology and Biotechnology (IMBB).

 

… Research infrastructure complying with the activities of the home Institutions.

Business oriented  and exploitation tools operated through STEP-C (Science and Technology Park of Crete) and PRAXI created to provide a bridge between Research and Industry in Greece. 
. Adopting to the rapidly evolving needs of the region of Crete/ Greece, the research advancements at FORTH and the local Academic and Research Institutions, FORTH, through STEP-C offers, in addition to incubating facilities and services to start up companies with new and emerging technologies, specialized professional services that are difficult to find under one roof and geared to assisting and guiding companies to:

Unleash their potential through innovation
Assess and secure their intellectual capital
Support better their business interests and needs
Transfer their technological advancements into the manufacturing of innovative products and services

. Yes. service.

Sectors
Technology

NATIONAL INSTITUTE OF CHEMISTRY SLOVENIA / KEMIJSKI INSTITUT

Slovenia: West Slovenia

Overview

Mission/Objectives of the cluster organisation

National Institute of Chemistry, Ljubljana, Slovenia (NIC), is a leading Slovenian research institution in the field of chemistry and related disciplines. Basic and applied research are oriented towards fields which are of long-term importance to both Slovenia and the world: biotechnology, environmental protection, structural and theoretical chemistry, analytical chemistry, materials research, and chemical engineering, through which the institute is in line with the needs of the domestic chemical, pharmaceutical, tire, and food industries. The work of the Institute is also in line with the priority thematic areas of the EU Research and Innovation programme Horizon 2020. NIC has 300 employees of which around 266 carry out research work in 14 laboratories and two infrastructure centres; 136 of these have doctorates of science degrees. The Institute was the first research institution in Slovenia to obtain ISO 9001 standards in December 2003 with the goal of improving the conditions, as well as organization… NIC owns some pieces of equipment that are unique for the Slovene research area and in the “new member states” area:

AR STEM – state of the art atomic resolution scanning transmission electron microscope

Karl Zeiss Supra 35 VP Electronic Microscope with EDX analysis-

a high resolution powder x-ray diffractometer,

a 800, 600, 400 MHz NMR spectrometer

. Research and development expertizes od NIC departments, which are also interesting for the cooperation with industry, can be found at the following links:

Computer simulations

life sciences and bioinformatics
chemometrics and statistical methods in chemistry, proteomics and genomics
studies of links between the structure and function of complex molecular systems

Materials

analysis and synthesis of polymeric materials
development of porous adsorbents and porous catalysts
development of heterogeneous catalysts
development of advanced batteries
development of coatings

Chemical technology and engineering

development and optimization of chemical processes
wastewater cleaning

Chemical analysis

inorganic materials and ionic species
chemical and biochemical analysis of water
substances in food supplements
development, validation and analysis of active pharmaceutical ingredients and products  according to GMP standard
characterization of chemical…. Yes. service.

Sectors
Technology